Epstein-Barr virus-associated methotrexate-induced accelerated rheumatoid nodulosis.

Methotrexate-induced accelerated nodulosis in a patient with rheumatoid arthritis and scleroderma.

Methotrexate-induced nodulosis.

©2015 8872147 Canada Inc. or its licensors CMAJ, July 14, 2015, 187(10) E327 A 52-year-old woman with a seven-year history of seropositive rheumatoid arthritis treated with oral prednisolone (5 mg/d) and methotrexate (6 mg/wk) presented after two weeks of experiencing rapidly increasing tender eruptions on her fingers. Clinical examination showed multiple skin-coloured hard nodules of up to 15 ...

Methotrexate induced accelerated nodulosis.

Methotrexate induced accelerated nodulosis (MIAN) is a rare but unique side effect of methotrexate therapy. There is paucity of data from our country about this entity. We analyzed 14 cases of MIAN and studied its association with gender, rheumatoid factor positivity and dose and duration of methotrexate. Fourteen patients (8 females), 12 with rheumatoid arthritis (8 seropositive), one each wit...

Methotrexate-induced CD30+ T-cell lymphoproliferative disorder of the oral cavity

EBER: Epstein-Barr encoded RNA EBV: Epstein-Barr virus LPD: lymphoproliferative disorder MTX: methotrexate RA: rheumatoid arthritis INTRODUCTION For more than 30 years, methotrexate (MTX) has been a mainstay in the treatment of various inflammatory disorders including rheumatoid arthritis (RA) and psoriasis. Off-label use of MTX has expanded in recent years, as it is found to be effective in tr...

THE IN VITRO GROWTH PROPERTIES OF CELL LINES FROM EPSTEIN-BARR VIRUS-INDUCED TAMARIN TUMORS AND TAMARIN B CELLS TR ANSFORMED BY EPSTEIN BARR VIRUS

EBV-carrying human cell lines, depending on whether the cells are derived from Burkitt's lymphoma (BL) tumor biopsies or transformed by EBV in vitro, have different growth properties in vitro. In contrast, there are no clear differences between tamarin tumor lines and tamarin LCLs in vitro. Both types of tamarin cell lines could grow in agarose and formed colonies unlike human LCLs, althoug...